產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)
Cat. Number:
Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗體XY-5193R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 beingAnti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗體 approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.
Also known as:
phospho-AKT1/AKT2/AKT3 (Tyr315+Tyr316+Tyr312); Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗體AKT1/AKT2/AKT3(phospho-Tyr315/316/312); AKT1/2/3 (phospho Y315 + Y316 + Y312); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; AKT 2; AKT2; AKT-2; AKT2_HUMAN; AKT 3; AKT3; AKT-3; AKT3_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PKB beta; PKB gamma; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗體Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human AKT1 around the phosphorylation site of Tyr315.
●
Predicted Molecular Weight: 56kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗體must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗體must be determined by the end user.
xy-11883R MAP3K4絲裂原活化蛋白激酶激酶激酶4抗體
xy-11884R NEUROD6神經(jīng)細(xì)胞分化因子6抗體
xy-11885R MEIS2同源盒蛋白Meis2抗體
xy-11886R METRNMeteorin神經(jīng)膠質(zhì)細(xì)胞分化調(diào)節(jié)蛋白抗體
xy-11887R MPP5棕櫚?；さ鞍?抗體
xy-11888R MPPED2腦蛋白239抗體
xy-11889R Meis homeobox 3同源盒蛋白MEIS3抗體
xy-11891R Myotrophin顆粒細(xì)胞分化蛋白抗體
xy-11890R Monoamine oxidase A+B單氨氧化酶A+B抗體
xy-12039R MIR16膜蛋白相互作用蛋白R(shí)GS16抗體
xy-8296R Matriptase 2膜型絲氨酸蛋白酶2抗體
xy-7870R MRP8+MRP14多藥耐藥相關(guān)蛋白8/9/14抗體
xy-7914R MOBKL2BMob1同源蛋白MOBKL2B抗體
xy-7915R MOBKL2CMob1同源蛋白MOBKL2C抗體
xy-7880R MEGF5復(fù)合型表皮生長(zhǎng)因子樣結(jié)構(gòu)域蛋白5抗體
xy-9674R MYLIP低密度脂蛋白受體的誘導(dǎo)降解蛋白抗體
xy-9673R ZNF144鋅指蛋白144抗體
xy-6936R MYF5生肌決定因子Myf5抗體
xy-8200R phospho-MYF5 (phospho Ser49)磷酸化生肌決定因子Myf5抗體
xy-11419R MRAP2黑素皮質(zhì)素2受體輔助蛋白2抗體
xy-4940R Metallothionein 3金屬硫蛋白3抗體
xy-9109R MAP4K6 絲裂原活化蛋白激酶MAP4K6抗體
xy-0266R MAP65擬南芥MAP65蛋白抗體
xy-11201R Musashi 1神經(jīng)干細(xì)胞RNA結(jié)合蛋白Musashi1抗體
