產(chǎn)品詳情
簡單介紹：
Anti-phospho-BAD (Ser75)抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-phospho-BAD (Ser75)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-BAD (Ser75)
Cat. Number:
Anti-phospho-BAD (Ser75)抗體KL-3009R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrialAnti-phospho-BAD (Ser75)抗體 membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of Anti-phospho-BAD (Ser75)抗體this gene results in two transcript variants which encode the same isoform.
Also known as:
Bad (phospho S75); Bad (phospho Ser75); p-Bad (S75);p- Bad (Ser75); p-Bad (phospho Ser75); BBC 2; BBC2; BBC6; Anti-phospho-BAD (Ser75)抗體Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X / BCL 2 Binding Protein; BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl-2-like protein 8; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl2-L-8; BCL2L8; BclXL; Proapoptotic BH3 Only Protein; BAD_HUMAN; Bcl-2-binding component 6.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Horse, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human BAD around the phosphorylation site of Ser75.
●
Predicted Molecular Weight: 22kDa.
Storage:
Shipped at 4℃, Store Anti-phospho-BAD (Ser75)抗體at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl017Bo01 上皮性鈣黏附蛋白(CDHE)多克隆抗體 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Ga01 上皮性鈣黏附蛋白(CDHE)多克隆抗體 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Hu01 上皮性鈣黏附蛋白(CDHE)多克隆抗體 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Mu01 上皮性鈣黏附蛋白(CDHE)多克隆抗體 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Po01 上皮性鈣黏附蛋白(CDHE)多克隆抗體 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Ra01 上皮性鈣黏附蛋白(CDHE)多克隆抗體 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl019Hu01 白介素8受體α(IL8Rα)多克隆抗體 Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)
kl019Mu01 白介素8受體α(IL8Rα)多克隆抗體 Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)
kl019Ra01 白介素8受體α(IL8Rα)多克隆抗體 Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)
kl019Rb51 白介素8受體α(IL8Rα)多克隆抗體 Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)
kl021Ga01 睫狀神經(jīng)營養(yǎng)因子(CNTF)多克隆抗體 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Hu01 睫狀神經(jīng)營養(yǎng)因子(CNTF)多克隆抗體 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Mu01 睫狀神經(jīng)營養(yǎng)因子(CNTF)多克隆抗體 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Po01 睫狀神經(jīng)營養(yǎng)因子(CNTF)多克隆抗體 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Ra01 睫狀神經(jīng)營養(yǎng)因子(CNTF)多克隆抗體 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Rb51 睫狀神經(jīng)營養(yǎng)因子(CNTF)多克隆抗體 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl022Bo01 血管內(nèi)皮細(xì)胞蛋白C受體(PROCR)多克隆抗體 Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
kl022Ga01 血管內(nèi)皮細(xì)胞蛋白C受體(PROCR)多克隆抗體 Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
kl022Hu01 血管內(nèi)皮細(xì)胞蛋白C受體(PROCR)多克隆抗體 Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
