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  • 產(chǎn)品名稱:Anti-Phospho-cdc2 (Thr161)抗體

  • 產(chǎn)品型號(hào):磷酸化周期素依賴激酶2抗體
  • 產(chǎn)品廠商:KALANG
  • 產(chǎn)品文檔:
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Anti-Phospho-cdc2 (Thr161)抗體產(chǎn)品質(zhì)量穩(wěn)定,實(shí)驗(yàn)效果明顯,貨期快,價(jià)格優(yōu)惠,歡迎垂詢訂購(gòu)!我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-Phospho-cdc2 (Thr161)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹:
Rabbit  Anti-Phospho-cdc2 (Thr161)
Cat. Number:
Anti-Phospho-cdc2 (Thr161)抗體KL-3481R
Quantity size:
0.1ml
Concentration:
1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The cell division control protein cdc2, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S phase and mitosis. Cdc2 exists as Anti-Phospho-cdc2 (Thr161)抗體a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.
Also known as:
CDC2(Phospho-Thr161); Anti-Phospho-cdc2 (Thr161)抗體P34CDC2; Cdc 2; CDK 1; CDK1; Cell division control protein 2; Cell division control protein 2 homolog; Cell division cycle 2 G1 to S and G2 to M; Cell Divsion Cycle 2 Protein.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, .
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human cdc2 around the phosphorylation site of Thr161 [VY(p-T)HE].
Predicted Molecular Weight: 34kDa.
Storage:
Shipped at 4℃, Store at -20℃ Anti-Phospho-cdc2 (Thr161)抗體(Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutionsAnti-Phospho-cdc2 (Thr161)抗體 must be determined by the end user.
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