產(chǎn)品詳情
簡單介紹：
Anti-beta-arrestin 1 + 2抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-beta-arrestin 1 + 2抗體用于**組化實驗,WB實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-beta-arrestin 1 + 2
Cat. Number:
Anti-beta-arrestin 1 + 2抗體XY-0857R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Beta Arrestin 1 is a Anti-beta-arrestin 1 + 2抗體member of a family of proteins that are widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling. It mediates agonist dependent desensitization and internalization of G protein coupled receptors (GPCRs, e.g., beta 2 adrenergic receptor). After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G protein receptor kinases (GRKs) on serine residues. Beta Arrestin 1 has important roles in the cytoplasm and at the plasma membrane in the desensitization and internalization of G protein coupled receptors (GPCRs) and is increasingly appreciated to play an important role in the endocytosis and signaling of GPCRs. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine 412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane. Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.
Also known as:
Beta arrestin 1; ARB 1; Anti-beta-arrestin 1 + 2抗體ARB1; ARR 1; ARR1; ARRB 1; ARRB1; Arrestin beta 1; ARRB1_HUMAN; Arrestin 2; Arrestin beta-1; Beta-arrestin-1; Beta-arrestin 2; Beta Arrestin 2; ARB 2; ARB2; ARR 2; ARR2; ARRB 2; ARRB2; ARRB2_HUMAN; Arrestin 3; Arrestin beta 2; Arrestin beta-2; BARR2; DKFZp686L0365; HGNC:712; Beta-arrestin-2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Beta-arrestin 1.
●
Predicted Molecular Weight: 45kDa.
Storage:
Shipped at 4℃,Anti-beta-arrestin 1 + 2抗體 Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 Anti-beta-arrestin 1 + 2抗體ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
xy-5987R ARL11ADP核糖基化因子樣11抗體
xy-5990R ARMCX3ARM重復(fù)X連鎖蛋白ARMCX3抗體
xy-5988R ARMCX1ARM重復(fù)X連鎖蛋白ARMCX1抗體
xy-5989R ARMCX2ARM重復(fù)X連鎖蛋白ARMCX2抗體
xy-5991R Apg10自噬相關(guān)蛋白10抗體
xy-6017R ACBD6?；o酶A結(jié)合結(jié)構(gòu)域蛋白6抗體
xy-6019R Aminoacylase 1氨基?；?抗體
xy-3831R Adipose Triglyceride Lipase脂肪甘油三酯脂酶抗體
xy-4002R phospho-AMPK alpha-1 (Thr172)磷酸化腺苷單磷酸活化蛋白激酶α1抗體
xy-3847R Amphiregulin雙調(diào)蛋白（結(jié)腸直腸細胞源性生長因子）抗體
xy-5185R phospho-AQP2(Ser264)磷酸化水通道蛋白2抗體
xy-5180R AXL粘附相關(guān)激酶抗體
xy-5181R phospho-AXL (Tyr698+Tyr702+Tyr703)磷酸化粘附相關(guān)激酶抗體
xy-5182R phospho-AKT1 + AKT2 + AKT3 (Thr308+Thr309+Thr305)磷酸化蛋白激酶B抗體
xy-5187R phospho-AQP2(Ser269)磷酸化水通道蛋白2抗體
xy-5186R phospho-Amyloid Precursor Protein (Thr743)磷酸化APP淀粉樣肽前體蛋白抗體
xy-5188R phospho-AKT1(Ser129)磷酸化蛋白激酶B抗體
xy-5189R phospho-Amyloid Precursor Protein (Ser198)磷酸化APP淀粉樣肽前體蛋白抗體
xy-5190R phospho-ATF4 (Ser245)磷酸化活化轉(zhuǎn)錄因子4抗體
xy-5191R phospho-Androgen Receptor (Ser213)磷酸化雄**受體抗體
xy-5192R phospho-Androgen Receptor (Ser650)磷酸化雄**受體抗體
xy-5193R phospho-AKT1+2+3 (Tyr315+316+312) 磷酸化蛋白激酶AKT1,2,3抗體
xy-5194R phospho-AKT1(Thr34)磷酸化蛋白激酶B抗體
xy-5195R phospho-ATF2(Ser472)磷酸化活化復(fù)制因子2抗體
xy-9806R APR3凋亡相關(guān)蛋白3抗體
xy-3871R ATG18自噬相關(guān)蛋白18抗體
