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產品詳情
  • 產品名稱:Anti-phospho-APE(Ser1417)抗體

  • 產品型號:磷酸化肌動蛋白結合蛋白Girdin抗體
  • 產品廠商:KALANG
  • 產品文檔:
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簡單介紹:
Anti-phospho-APE(Ser1417)抗體產品質量穩(wěn)定,實驗效果明顯,貨期快,價格優(yōu)惠,歡迎垂詢訂購!我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-APE(Ser1417)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹:
Rabbit  Anti-phospho-APE(Ser1417)
Cat. Number:
Anti-phospho-APE(Ser1417)抗體KL-6465R
Quantity size:
0.1ml
Concentration:
1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Plays a role as a key Anti-phospho-APE(Ser1417)抗體modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ***** neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.
Also known as:
Girdin (phospho S1417); Anti-phospho-APE(Ser1417)抗體p-APE(Ser1417); Akt phosphorylation enhancer; APE; Coiled coil domain containing protein 88A; G alpha interacting vesicle associated protein; Girders of actin filament; GIV; HkRP1; Hook related protein 1; AKT iphosphorylation enhancer; Akt phosphorylation enhancer; Ccdc88a; GIV; GRDN; GRDN_HUMAN; HkRP1; Hook related protein 1; Hook-related protein 1; KIAA1212.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, .
Immunogen: KLH conjugated synthesised phosphopeptide derived from human APE around the phosphorylation site of Ser1417.
Predicted MolecularAnti-phospho-APE(Ser1417)抗體 Weight: 206kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-200   
Not yet tested in other applications. 
Optimal working Anti-phospho-APE(Ser1417)抗體dilutions must be determined by the end user.
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