產(chǎn)品詳情
簡單介紹：
Anti-Phospho-BRCA1 (Ser1524)抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Phospho-BRCA1 (Ser1524)抗體用于**組化實驗,WB實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-Phospho-BRCA1 (Ser1524)
Cat. Number:
Anti-Phospho-BRCA1 (Ser1524)抗體KL-3014R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, Anti-Phospho-BRCA1 (Ser1524)抗體and signal transducers to form a large multi-subunit protein complex known as BASC for BRCA1-associated genome surveillance complex. This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complex. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants have been described for this gene but only some have had their full-length natures identified. Transcript Variant: This variant (BRCA1a') uses different splice site in the 5' UTR when compared to variant BRCA1a. It encodes the full-length BRCA1 protein (isoform 1) which is also known as p220. Variants BRCA1a and BRCA1b also encode the full-length Anti-Phospho-BRCA1 (Ser1524)抗體BRCA1 protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Also known as:
BRCA1(Phospho-Ser1524); Anti-Phospho-BRCA1 (Ser1524)抗體BRCA1 (phospho S1524); p-BRCA1 (phospho S1524); BRCA 1; BRCA1; BRCA1/BRCA2 containing complex subunit 1; BRCA1/BRCA2-containing complex, subunit 1; BRCA1_HUMAN; BRCAI; BRAC 1; BRCA 1; BRCC 1; BRCC1; Breast Cancer 1; Breast Cancer 1 Early Onset; Breast cancer type 1 susceptibility protein; Breast and ovarian cancer susceptibility protein 1; Breast Ovarian Cancer Susceptibility; IRIS; Papillary Serous Carcinoma Of The Peritoneum; PSCP; RING finger protein 53; BROVCA1; IRIS; PNCA4; PPP1R53; Protein phosphatase 1 regulatory subunit 53; RNF53; BAP1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human BRCA1 around the phosphorylation site of Ser1524.
●
Predicted Molecular Weight: 205kDa.
Storage:
Shipped at 4℃, Store Anti-Phospho-BRCA1 (Ser1524)抗體at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl051Bo01 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl051Cp01 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl051Eq01 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl051Ga01 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl051Gu01 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl051Hu01 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl051Mu01 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl051Po01 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl051Ra01 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl051Rb51 胰島素樣生長因子2(IGF2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)
kl052Bo01 胰島素樣生長因子結(jié)合蛋白1(IGFBP1)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Cp01 胰島素樣生長因子結(jié)合蛋白1(IGFBP1)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Fi01 胰島素樣生長因子結(jié)合蛋白1(IGFBP1)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Ga01 胰島素樣生長因子結(jié)合蛋白1(IGFBP1)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Hu01 胰島素樣生長因子結(jié)合蛋白1(IGFBP1)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Mu01 胰島素樣生長因子結(jié)合蛋白1(IGFBP1)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Po01 胰島素樣生長因子結(jié)合蛋白1(IGFBP1)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl052Ra01 胰島素樣生長因子結(jié)合蛋白1(IGFBP1)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 1 (IGFBP1)
kl053Bo01 胰島素樣生長因子結(jié)合蛋白2(IGFBP2)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2)
