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產(chǎn)品詳情
  • 產(chǎn)品名稱:Anti-phospho-CBL2 (Tyr774)抗體

  • 產(chǎn)品型號(hào):磷酸化原癌蛋白CBL2抗體
  • 產(chǎn)品廠商:KALANG
  • 產(chǎn)品文檔:
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Anti-phospho-CBL2 (Tyr774)抗體產(chǎn)品質(zhì)量穩(wěn)定,實(shí)驗(yàn)效果明顯,貨期快,價(jià)格優(yōu)惠,歡迎垂詢訂購!我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-phospho-CBL2 (Tyr774)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹:
Rabbit  Anti-phospho-CBL2 (Tyr774)
Cat. Number:
Anti-phospho-CBL2 (Tyr774)抗體KL-3090R
Quantity size:
0.1ml
Concentration:
1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein Anti-phospho-CBL2 (Tyr774)抗體also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Mar 2012]
Also known as:
CBL2 (phospho-Tyr774); Anti-phospho-CBL2 (Tyr774)抗體CBL2 (phospho-Y774); p-CBL2 (Tyr774); p-CBL2 (Y774); C CBL; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B lineage lymphoma proto oncogene; CBL 2;E3 ubiquitin protein ligase CBL; Oncogene CBL2; Proto oncogene c CBL; RGD1561386; RING finger protein 55; RNF55v Signal transduction protein CBL; 4732447J05Rik; CBL_HUMAN.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Chicken, Pig, Rabbit, Sheep, .
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CBL2 around the phosphorylation site of Tyr774.
Predicted Molecular Weight:Anti-phospho-CBL2 (Tyr774)抗體 100kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions Anti-phospho-CBL2 (Tyr774)抗體must be determined by the end user.
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