產(chǎn)品詳情
簡單介紹：
Anti-phospho-CDKN1A (Thr145)抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-CDKN1A (Thr145)抗體用于**組化實驗,WB實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-CDKN1A (Thr145)
Cat. Number:
Anti-phospho-CDKN1A (Thr145)抗體KL-5237R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. Anti-phospho-CDKN1A (Thr145)抗體The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically.
Also known as:
p21 (phospho T145); p-p21Anti-phospho-CDKN1A (Thr145)抗體 (phospho T145); p21Cip1 (Phospho-Thr145); Activating Fragment 1; CAP20; Cation chloride cotransporter-interacting protein 1; CDK Interacting Protein 1; CDK-interacting protein 1; CDKI; CDKN 1; CDKN1; CDKN1A; CIP1; Cyclin Dependent Kinase Inhibitor 1A; Cyclin-dependent kinase inhibitor 1; Cyclin-dependent kinase inhibitor 1A (P21); Cyclin-dependent kinase inhibitor 1A (p21, Cip1); DNA Synthesis Inhibitor; MDA 6; MDA-6; MDA6; Melanoma Differentiation Associated Protein 6; Melanoma differentiation-associated protein 6; Melanoma differentiation-associated protein; p21; P21 protein; p21CIP1; p21WAF; PIC1; SDI1; SLC12A9; WAF1; Wildtype p53 Activating Fragment 1; Wildtype p53-activated fragment 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .Anti-phospho-CDKN1A (Thr145)抗體
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CDKN1A around the phosphorylation site of Thr145 [RQ(p-T)S].
●
Predicted Molecular Weight: 18kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be Anti-phospho-CDKN1A (Thr145)抗體determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be Anti-phospho-CDKN1A (Thr145)抗體determined by the end user.
kl728Hu01 生長分化因子2(GDF2)多克隆抗體 Polyclonal Antibody to Growth Differentiation Factor 2 (GDF2)
kl728Mu01 生長分化因子2(GDF2)多克隆抗體 Polyclonal Antibody to Growth Differentiation Factor 2 (GDF2)
kl729Hu01 癌蛋白誘導(dǎo)轉(zhuǎn)錄物3(OIT3)多克隆抗體 Polyclonal Antibody to Oncoprotein Induced Transcript 3 (OIT3)
kl735Hu01 胱天蛋白酶4(CASP4)多克隆抗體 Polyclonal Antibody to Caskle 4 (CASP4)
kl737Hu01 信號傳導(dǎo)轉(zhuǎn)錄激活因子6(STAT6)多克隆抗體 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 6 (STAT6)
kl744Hu01 泛素D(UBD)多克隆抗體 Polyclonal Antibody to Ubiquitin D (UBD)
kl745Hu01 血小板型磷酸果糖激酶(PFKP)多克隆抗體 Polyclonal Antibody to Phosphofructokinase, Platelet (PFKP)
kl750Hu01 腫瘤壞死因子配體超家族成員13(TNFSF13)多克隆抗體 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13)
kl750Mu01 腫瘤壞死因子配體超家族成員13(TNFSF13)多克隆抗體 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13)
kl752Hu01 Ⅰ類主要組織相容性復(fù)合體E(MHCE)多克隆抗體 Polyclonal Antibody to Major Histocomklibility Complex Class I E (MHCE)
kl753Hu01 谷氨酸受體相互作用蛋白1(GRIP1)多克隆抗體 Polyclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1)
kl756Hu01 表皮轉(zhuǎn)谷氨酰胺酶(TGM3)多克隆抗體 Polyclonal Antibody to Transglutaminase 3, Epidermal (TGM3)
kl757Hu01 肌動蛋白束蛋白(FSCN)多克隆抗體 Polyclonal Antibody to Fascin (FSCN)
kl758Hu01 核糖核酸酶A3(RNASE3)多克隆抗體 Polyclonal Antibody to Ribonuclease A3 (RNASE3)
