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產(chǎn)品詳情
  • 產(chǎn)品名稱:Anti-RFC2抗體

  • 產(chǎn)品型號:復制激活因子C2抗體
  • 產(chǎn)品廠商:KALANG
  • 產(chǎn)品文檔:
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簡單介紹:
Anti-RFC2抗體產(chǎn)品質(zhì)量穩(wěn)定,實驗效果明顯,貨期快,價格優(yōu)惠,歡迎垂詢訂購!我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-RFC2抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹:
Rabbit  Anti-RFC2
Cat. Number:
Anti-RFC2抗體KL-11305R
Quantity size:
0.2ml
Concentration:
1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Replication factor C (RFC) is an essential DNA polymerase accessory protein that is required for numerous aspects of DNA metabolism including DNA replication, DNA repair, and telomere metabolism. RFC is a heteropentameric complex that recognizes a primer on a template DNA, binds to a primer terminus, and loads Anti-RFC2抗體proliferating cell nuclear antigen (PCNA) onto DNA at primer-template junctions in an ATP-dependent reaction. All five of the RFC subunits share a set of related sequences (RFC boxes) that include nucleotide-binding consensus sequences. Four of the five RFC genes (RFC1, RFC2, RFC3, and RFC4) have consensus ATP-binding motifs. The small RFC proteins, RFC2, RFC3, RFC4 and RFC5, interact with Rad24, whereas the RFC1 subunit does not. RFC2, the third-largest subunit of the RFC complex, exhibits ATP binding which makes it important for both DNA replication and checkpoint function. The human RFC2 gene maps to chromosome 7q11.23 and encodes the RFC2 subunit. RFC2 has been associated with Williams-Beuren syndrome, which is a rare multi-system developmental disorder caused by the deletion of contiguous genes at 7q11.23.
Also known as:
Activator 1; Activator 1 subunit 2; Activator Anti-RFC2抗體140 kDa Subunit; MGC3665; OTTHUMP00000160645; OTTHUMP00000160646; replication factor C (activator 1) 2 40kDa; Replication factor C (activator 1) 2; Replication factor C 2; Replication Factor C 40 kDa subunit; Replication factor C subunit 2; replication factor c2; Replication Factor C40 kDa subunit; RF C 40 kDa subunit; RF-C 40 kDa subunit; RFC 2; RFC 40; RFC 40 kDa subunit; RFC2; RFC2_HUMAN; RFC40; A1 40 kDa subunit; A1 antibody A140; Activator 1 40 kDa Subunit.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .
Immunogen: KLH conjugated syntheticAnti-RFC2抗體 peptide derived from human RFC2.
Predicted Molecular Weight: 39kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. Anti-RFC2抗體
Optimal working dilutions must be determined by the end user.

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